The FibrinoGENIE 57 is a temperature controlled thermoblock with 6 tube holders, heated to exactly 57°C. The unit facilitates the effortless heating of tubes filled with EDTA-anticoagulated blood and therefore eliminates the need for a bulky water bath during the determination of fibrinogen concentration of the plasma.

The fibrinogen concentration of the plasma is increasingly recognized as an index of non-specific inflammation. The only coagulation testing performed by Clinical Pathology is Schalm's Fibrinogen [1]. This test is performed on EDTA samples only and is used for determination of fibrinogen concentration as an indicator of inflammation in large animals. In short, the method is as follows:

Two microhematocrit tubes are filled with EDTA-anticoagulated blood. One is centrifuged and the total protein in the plasma is measured. The second tube is heated at 57°C for 3 minutes, which precipitates the fibrinogen. The second tube is then centrifuged and the protein result read similarly. The protein result in the heated tube is subtracted from the result in the unheated tube; the difference is equivalent to the fibrinogen that was removed from the plasma in the second tube by heating and centrifuging.

[1]  N. C. Jain (1986), Schalm's Veterinary Hematology, 4th Edition, pp. 58-59

• Short heat-up time
• Compact size and lightweight
• Easy transportable 
• Straightforward handling